ethyl 4,4,4-trichlorobutanoate
ethyl 4,4,4-trichlorobutanoate
CAS: 20101-80-8
Molecular Formula: C6H9Cl3O2
ethyl 4,4,4-trichlorobutanoate - Names and Identifiers
| Name | ethyl 4,4,4-trichlorobutanoate |
| Synonyms | NSC 299167 Ethyl 4,4,4-trichlorobutyrate Ethyl 4,4,4-trichlorobutanoate ethyl 4,4,4-trichlorobutanoate Butanoic acid, 4,4,4-trichloro-, ethyl ester |
| CAS | 20101-80-8 |
| InChI | InChI=1/C6H9Cl3O2/c1-2-11-5(10)3-4-6(7,8)9/h2-4H2,1H3 |
ethyl 4,4,4-trichlorobutanoate - Physico-chemical Properties
| Molecular Formula | C6H9Cl3O2 |
| Molar Mass | 219.49 |
| Density | 1.328±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 74℃ (0.13 Torr) |
| Flash Point | 89.6±24.9℃ |
| Vapor Presure | 0.063mmHg at 25°C |
| Refractive Index | 1.4660 (589.3 nm 20℃ |
ethyl 4,4,4-trichlorobutanoate - Introduction
ethyl 4,4,4-trichlorobutanoate, also known as 4,4, 4-trichlorobutyl acetate, is an organic compound with the chemical formula Cl3C(CH2)2CO2CH3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: ethyl 4,4,4-trichlorobutanoate is a colorless liquid.
-Boiling point: Its boiling point is 155-156 degrees Celsius.
-Density: The relative density is 1.466.
-Solubility: It is easily soluble in organic solvents, such as alcohols and ethers, and insoluble in water.
Use:
- ethyl 4,4,4-trichlorobutanoate is commonly used as a reagent and solvent for organic synthesis, for esterification, dehydration, acylation, etc.
-It is also commonly used in the removal of carboxylic acid protecting groups in organic synthesis, such as the deethylation of carboxylic acids.
-In addition, ethyl 4,4,4-trichlorobutanoate can also be used for some reactions in the dye and pharmaceutical industries.
Method:
- ethyl 4,4,4-trichlorobutanoate can be obtained by esterification of 4,4,4-trichlorobutanoic acid with ethanol. In the esterification reaction, hydrochloric acid may be used as a catalyst.
Safety Information:
- ethyl 4,4,4-trichlorobutanoate is an organic solvent with certain toxicity. Contact with skin, eyes or inhalation of vapors may cause irritation.
-Avoid contact with oxidants during use and storage to prevent fire or explosion.
-Be careful to use appropriate protective equipment such as goggles, gloves and protective clothing.
-Avoid contact with fire during storage or handling, and store in a cool, well-ventilated place.
Nature:
-Appearance: ethyl 4,4,4-trichlorobutanoate is a colorless liquid.
-Boiling point: Its boiling point is 155-156 degrees Celsius.
-Density: The relative density is 1.466.
-Solubility: It is easily soluble in organic solvents, such as alcohols and ethers, and insoluble in water.
Use:
- ethyl 4,4,4-trichlorobutanoate is commonly used as a reagent and solvent for organic synthesis, for esterification, dehydration, acylation, etc.
-It is also commonly used in the removal of carboxylic acid protecting groups in organic synthesis, such as the deethylation of carboxylic acids.
-In addition, ethyl 4,4,4-trichlorobutanoate can also be used for some reactions in the dye and pharmaceutical industries.
Method:
- ethyl 4,4,4-trichlorobutanoate can be obtained by esterification of 4,4,4-trichlorobutanoic acid with ethanol. In the esterification reaction, hydrochloric acid may be used as a catalyst.
Safety Information:
- ethyl 4,4,4-trichlorobutanoate is an organic solvent with certain toxicity. Contact with skin, eyes or inhalation of vapors may cause irritation.
-Avoid contact with oxidants during use and storage to prevent fire or explosion.
-Be careful to use appropriate protective equipment such as goggles, gloves and protective clothing.
-Avoid contact with fire during storage or handling, and store in a cool, well-ventilated place.
Last Update：2024-04-10 22:29:15
